Consultants

Magnus Ingelman-Sundberg, Ph.D. (Consultant)
http://ki.se/ki/jsp/polopoly.jsp?d=9785&l=en
is Professor of Physiology and Pharmacology, and Head of the Section of Pharmacogenetics at the Karolinska Institute in Sweden. He is the Chairman of the Editorial Board for Pharmacogenetics and Genomics. In 2008 he was named to the Nobel Assembly. Dr. Ingelman-Sundberg has authored over 350 original publications. Dr. Ingelman-Sundberg's research has focused on the function, regulation, and pharmacogenetics of CYP. He has emerged as a leading scientist in characterizing novel CYP polymorphisms and elucidating their clinical significance. Among his pioneering findings is the importance of CYP2D6 gene duplications in causing an ultrarapid metabolizer phenotype that renders patients non-responsive to antidepressants and prone to adverse effects of codeine. His laboratory is currently pursuing genetic as well as epigenetic reasons for interindividual variability CYP3A4 and CYP1A2 expression. Recently his group identified new extrahepatic CYPs that are overexpressed in certain cancer cells and may prove to be novel drug targets. He will be involved in the development of the education curriculum focusing on pharmacogenomics primer concepts and clinical applications in concentrated therapeutic areas.

Karen S. Hudmon, Dr.P.H., M.S., R.Ph. (Consultant)
http://www.phpr.purdue.edu/facstaff/?uid=khudmon
is Associate Professor, School of Pharmacy and Pharmaceutical Sciences, Purdue University. Dr. Hudmon's research involves (1) the study of predictors of smoking among adolescents and young adults; (2) the treatment of tobacco use and dependence through expansion of the clinician's role in cessation; (3) understanding genetics as they relate to tobacco use and dependence; and (4) medication compliance for chronic disease. She has co-coordinated an effort to develop, evaluate, and disseminate a comprehensive tobacco cessation training program, Rx for Change: Clinician-Assisted Tobacco Cessation, for students in the health professions. This program is being disseminated to health professional schools across the US and has witnessed broadscale adoption. She will assist in evaluation of the education program to the different audience groups and delivery methods.